(BCN/KRON) — A wrong-way driver is suspected of driving under the influence and causing a crash that left two people dead in Los Altos Hills early Saturday morning, the California Highway Patrol confirmed to KRON4.

Around 1 a.m., a driver in a Honda Civic was heading in the wrong direction on southbound Interstate 280 near the El Monte Road off ramp when they collided head on with a Toyota Avalon.

There were two people inside of the Honda, and they both suffered fatal injuries and were declared dead at the scene. The driver and passenger of the Toyota suffered major injuries in the crash.

Both occupants in the Toyota are in their 40s and were taken to a local hospital for treatment. The roadway was cleared and reopened just before 6 a.m., CHP said.